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Separation of inhibition and activation of the allosteric yeast chorismate mutase

Yeast chorismate mutase (EC 5.4.99.5) shows homotropic activation by the substrate, allosteric activation by tryptophan, and allosteric inhibition by tyrosine. In this study mutants of chorismate mutase have been found that remain sensitive to one allosteric effector (tryptophan) but insensitive to...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Schnappauf, Georg, Lipscomb, William N., Braus, Gerhard H.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19661/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9501182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.6.2868
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