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Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor

Type I human diabetics and streptozotocin-induced diabetic mice with higher genetically determined levels of angiotensin-converting enzyme have an increased risk of developing nephropathy. However, previous experiments in mice and computer simulations indicate that modest increases in angiotensin-co...

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Autors principals: Kakoki, Masao, Takahashi, Nobuyuki, Jennette, J. Charles, Smithies, Oliver
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC516527/
https://ncbi.nlm.nih.gov/pubmed/15326315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405449101
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