Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice

An insertion polymorphism of the angiotensin-I converting enzyme gene (ACE) is common in humans and the higher expressing allele is associated with an increased risk of diabetic complications. The ACE polymorphism does not significantly affect blood pressure or angiotensin II levels, suggesting that...

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Detalhes bibliográficos
Main Authors: Kakoki, Masao, Sullivan, Kelli A., Backus, Carey, Hayes, John M., Oh, Sang Su, Hua, Kunjie, Gasim, Adil M. H., Tomita, Hirofumi, Grant, Ruriko, Nossov, Sarah B., Kim, Hyung-Suk, Jennette, J. Charles, Feldman, Eva L., Smithies, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890475/
https://ncbi.nlm.nih.gov/pubmed/20479236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005144107
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