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Low TGFβ1 expression prevents and high expression exacerbates diabetic nephropathy in mice

Nephropathy develops in many but not all patients with long-standing type 1 diabetes. Substantial efforts to identify genotypic differences explaining this differential susceptibility have been made, with limited success. Here, we show that the expression of the transforming growth factor β1 gene (T...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hathaway, Catherine K., Gasim, Adil M. H., Grant, Ruriko, Chang, Albert S., Kim, Hyung-Suk, Madden, Victoria J., Bagnell, C. Robert, Jennette, J. Charles, Smithies, Oliver, Kakoki, Masao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426439/
https://ncbi.nlm.nih.gov/pubmed/25902541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504777112
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