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Prolactin alters blood pressure by modulating the activity of endothelial nitric oxide synthase

Increased levels of a cleaved form of prolactin (molecular weight 16 kDa) have been associated with preeclampsia. To study the effects of prolactin on blood pressure (BP), we generated male mice with a single-copy transgene (Tg; inserted into the hypoxanthine-guanine phosphoribosyltransferase locus)...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Chang, Albert S., Grant, Ruriko, Tomita, Hirofumi, Kim, Hyung-Suk, Smithies, Oliver, Kakoki, Masao
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5098649/
https://ncbi.nlm.nih.gov/pubmed/27791173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1615051113
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