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Effect of methylguanidine on rat blood pressure: role of endothelial nitric oxide synthase.

1. The effect of acute i.v. administration of methylguanidine (MG) on mean arterial blood pressure (MABP) was investigated in anaesthetized male Wistar rats. 2. MG (1-30 mg kg-1 i.v.) produced an increase in MABP in a dose-dependent manner both in normal and in hexamethonium (5 mg kg-1, i.v)-treated...

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Autors principals: Sorrentino, R., Pinto, A.
Format: Artigo
Idioma:Inglês
Publicat: 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908399/
https://ncbi.nlm.nih.gov/pubmed/7582465
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