AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats

BACKGROUND AND PURPOSE: Nitric oxide (NO) plays an important role in endothelial function, and impaired NO production is involved in hypertension. Therefore, compounds that regulate endothelial NO synthase (eNOS) may be of therapeutic benefit. A novel, low molecular weight compound AVE3085 is a rece...

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Main Authors: Yang, Qin, Xue, Hong-Mei, Wong, Wing-Tak, Tian, Xiao-Yu, Huang, Yu, Tsui, Stephen KW, Ng, Patrick KS, Wohlfart, Paulus, Li, Huige, Xia, Ning, Tobias, Silke, Underwood, Malcolm John, He, Guo-Wei
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2011
主題:
Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130953/
https://ncbi.nlm.nih.gov/pubmed/21385179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01308.x
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