AVE3085, an enhancer of endothelial nitric oxide synthase, restores endothelial function and reduces blood pressure in spontaneously hypertensive rats

BACKGROUND AND PURPOSE: Nitric oxide (NO) plays an important role in endothelial function, and impaired NO production is involved in hypertension. Therefore, compounds that regulate endothelial NO synthase (eNOS) may be of therapeutic benefit. A novel, low molecular weight compound AVE3085 is a rece...

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Bibliografske podrobnosti
Main Authors: Yang, Qin, Xue, Hong-Mei, Wong, Wing-Tak, Tian, Xiao-Yu, Huang, Yu, Tsui, Stephen KW, Ng, Patrick KS, Wohlfart, Paulus, Li, Huige, Xia, Ning, Tobias, Silke, Underwood, Malcolm John, He, Guo-Wei
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2011
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130953/
https://ncbi.nlm.nih.gov/pubmed/21385179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01308.x
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