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Effect of methylguanidine on rat blood pressure: role of endothelial nitric oxide synthase.

1. The effect of acute i.v. administration of methylguanidine (MG) on mean arterial blood pressure (MABP) was investigated in anaesthetized male Wistar rats. 2. MG (1-30 mg kg-1 i.v.) produced an increase in MABP in a dose-dependent manner both in normal and in hexamethonium (5 mg kg-1, i.v)-treated...

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Detalhes bibliográficos
Main Authors: Sorrentino, R., Pinto, A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1908399/
https://ncbi.nlm.nih.gov/pubmed/7582465
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