Elevated blood pressures in mice lacking endothelial nitric oxide synthase

Nitric oxide produced in endothelial cells affects vascular tone. To investigate the role of endothelial nitric oxide synthase (eNOS) in blood pressure regulation, we have generated mice heterozygous (+/−) or homozygous (−/−) for disruption of the eNOS gene. Immunohistochemical staining with anti-eN...

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Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Shesely, Edward G., Maeda, Nobuyo, Kim, H.-S., Desai, Kaushik M., Krege, John H., Laubach, Victor E., Sherman, Paula A., Sessa, William C., Smithies, Oliver
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1996
Предметы:	Biological Sciences
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24066/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8917564/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.23.13176
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