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Transforming growth factor-β1 and diabetic nephropathy
Transforming growth factor-β1 (TGF-β1) is established to be involved in the pathogenesis of diabetic nephropathy. The diabetic milieu enhances oxidative stress and induces the expression of TGF-β1. TGF-β1 promotes cell hypertrophy and extracellular matrix accumulation in the mesangium, which decreas...
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Publicado no: | Am J Physiol Renal Physiol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Physiological Society
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835922/ https://ncbi.nlm.nih.gov/pubmed/26719364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00502.2015 |
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