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Transforming growth factor-β1 and diabetic nephropathy
Transforming growth factor-β1 (TGF-β1) is established to be involved in the pathogenesis of diabetic nephropathy. The diabetic milieu enhances oxidative stress and induces the expression of TGF-β1. TGF-β1 promotes cell hypertrophy and extracellular matrix accumulation in the mesangium, which decreas...
Gorde:
| Argitaratua izan da: | Am J Physiol Renal Physiol |
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| Egile Nagusiak: | , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Physiological Society
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4835922/ https://ncbi.nlm.nih.gov/pubmed/26719364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00502.2015 |
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