Kinetic control of dimer structure formation in amyloid fibrillogenesis
Amyloid fibril formation involves nonfibrillar oligomeric intermediates, which are important as possible cytotoxic species in neurodegenerative diseases. However, their transient nature and polydispersity have made it difficult to identify their formation mechanism or structure. We have investigated...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC516495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15326301/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402634101 |
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