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Temperature dependence of amyloid β-protein fibrillization

Fibrillogenesis of the amyloid β-protein (Aβ) is believed to play a central role in the pathogenesis of Alzheimer’s disease. Previous studies of the kinetics of Aβ fibrillogenesis showed that the rate of fibril elongation is proportional to the concentration of monomers. We report here the study of...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kusumoto, Yoko, Lomakin, Aleksey, Teplow, David B., Benedek, George B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1998
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22822/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9770477/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.21.12277
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