Structure determination of micelle-like intermediates in amyloid β-protein fibril assembly by using small angle neutron scattering

Increasing evidence supports the hypothesis that amyloid β-protein (Aβ) assembly is a key pathogenic feature of Alzheimer's disease. Thus, understanding the assembly process offers opportunities for the development of strategies for treating this devastating disease. In prior studies, Aβ was found t...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Yong, Winnie, Lomakin, Aleksey, Kirkitadze, Marina D., Teplow, David B., Chen, Sow-Hsin, Benedek, George B.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2001
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC117530/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11756677/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.012584899
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