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Structure determination of micelle-like intermediates in amyloid β-protein fibril assembly by using small angle neutron scattering
Increasing evidence supports the hypothesis that amyloid β-protein (Aβ) assembly is a key pathogenic feature of Alzheimer's disease. Thus, understanding the assembly process offers opportunities for the development of strategies for treating this devastating disease. In prior studies, Aβ was fo...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC117530/ https://ncbi.nlm.nih.gov/pubmed/11756677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.012584899 |
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