Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs

RATIONALE: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a potentially lethal arrhythmic disorder caused by mutations in the type-2 ryanodine receptor (RyR2). Mutant RyR2 cause abnormal Ca(2+) leak from the sarcoplasmic reticulum (SR), which is associated with the development of ar...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Cardiol
Autori principali: Li, Na, Wang, Qiongling, Sibrian-Vazquez, Martha, Klipp, Robert C., Reynolds, Julia O., Word, Tarah A., Scott, Larry, Salama, Guy, Strongin, Robert M., Abramson, Jonathan J., Wehrens, Xander H.T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5164850/
https://ncbi.nlm.nih.gov/pubmed/27838126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2016.10.078
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi