The anti-inflammatory role of extranuclear apurinic/apyrimidinic endonuclease 1/redox effector factor-1 in reactive astrocytes

Apurinic/apyrimidinic endonuclease 1 (APE1), a ubiquitous multipurpose protein, is also known as redox effector factor-1 (Ref-1). It is involved in DNA repair and redox signaling and, in turn, oxidative stress-induced neurodegeneration. Although previous studies have demonstrated that APE1/Ref-1 fun...

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Veröffentlicht in:Mol Brain
Hauptverfasser: Baek, Hyunjung, Lim, Chae Seong, Byun, Hee Sun, Cho, Hyun Sil, Lee, Yu Ran, Shin, Yong Sup, Kim, Hyun-Woo, Jeon, Byeong Hwa, Kim, Dong Woon, Hong, Jinpyo, Hur, Gang Min, Park, Jin Bong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5162091/
https://ncbi.nlm.nih.gov/pubmed/27986089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-016-0280-9
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