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Polyubiquitination of Apurinic/Apyrimidinic Endonuclease 1 by Parkin
Apurinic/apyrimidinic endonuclease 1 (APE1) is an essential protein crucial for repair of oxidized DNA damage not only in genomic DNA but also in mitochondrial DNA. Parkin, a tumor suppressor and Parkinson’s disease (PD) associated gene, is an E3 ubiquitin ligase crucial for mitophagy. While DNA dam...
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| Publicado no: | Mol Carcinog |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5379662/ https://ncbi.nlm.nih.gov/pubmed/27148961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22495 |
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