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RNA-cleaving properties of human apurinic/apyrimidinic endonuclease 1 (APE1)

We have recently identified apurinic/apyrimidinic endonuclease 1 (APE1) as an endoribonuclease that cleaves c-myc mRNA in vitro and regulates c-myc mRNA levels and half-life in cells. This study was undertaken to further unravel the RNA-cleaving properties of APE1. Here, we show that APE1 cleaves RN...

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Bibliographic Details
Main Authors: Kim, Wan-Cheol, King, Dustin, Lee, Chow H.
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180037/
https://ncbi.nlm.nih.gov/pubmed/21968700
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