PAR1 Scaffolds TGFβRII to Downregulate TGF-β Signaling and Activate ESC Differentiation to Endothelial Cells

We studied the function of the G-protein-coupled receptor PAR1 in mediating the differentiation of mouse embryonic stem cells (mESCs) to endothelial cells (ECs) that are capable of inducing neovascularization. We observed that either deletion or activation of PAR1 suppressed mouse embryonic stem cel...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Gong, Haixia, An, Shejuan, Sassmann, Antonia, Liu, Menglin, Mastej, Victoria, Mittal, Manish, Zhang, Wei, Hong, Zhigang, Offermanns, Stefan, Rehman, Jalees, Malik, Asrar B.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5161529/
https://ncbi.nlm.nih.gov/pubmed/27866874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.10.006
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker