Type III TGF-β receptor-independent signalling of TGF-β2 via TβRII-B, an alternatively spliced TGF-β type II receptor

Transforming growth factor-β (TGF-β) signals through membrane-bound serine/threonine kinase receptors, which upon stimulation phosphorylate Smad proteins and thereby trigger their nuclear translocation and transcriptional activity. Although the three mammalian isoforms of TGF-β are highly homologous...

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Hlavní autoři: Rotzer, Diana, Roth, Martin, Lutz, Marion, Lindemann, Dirk, Sebald, Walter, Knaus, Petra
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC133482/
https://ncbi.nlm.nih.gov/pubmed/11157754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.3.480
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