Type III TGF-β receptor-independent signalling of TGF-β2 via TβRII-B, an alternatively spliced TGF-β type II receptor

Transforming growth factor-β (TGF-β) signals through membrane-bound serine/threonine kinase receptors, which upon stimulation phosphorylate Smad proteins and thereby trigger their nuclear translocation and transcriptional activity. Although the three mammalian isoforms of TGF-β are highly homologous...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Rotzer, Diana, Roth, Martin, Lutz, Marion, Lindemann, Dirk, Sebald, Walter, Knaus, Petra
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2001
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11157754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.3.480
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