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TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs
Transforming growth factor (TGF)-βs are dimeric polypeptides that have vital roles in regulating cell growth and differentiation. They signal by assembling a receptor heterotetramer composed of two TβRI:TβRII heterodimers. To investigate whether the two heterodimers bind and signal autonomously, one...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3094126/ https://ncbi.nlm.nih.gov/pubmed/21423151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.54 |
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