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DR3 signaling modulates the function of Foxp3(+) regulatory T cells and the severity of acute graft-versus-host disease
CD4(+)Foxp3(+) regulatory T cells (Treg) are a subpopulation of T cells, which regulate the immune system and enhance immune tolerance after transplantation. Donor-derived Treg prevent the development of lethal acute graft-versus-host disease (GVHD) in murine models of allogeneic hematopoietic stem...
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| 發表在: | Blood |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5159706/ https://ncbi.nlm.nih.gov/pubmed/27760760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-723783 |
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