DR3 signaling modulates the function of Foxp3(+) regulatory T cells and the severity of acute graft-versus-host disease

CD4(+)Foxp3(+) regulatory T cells (Treg) are a subpopulation of T cells, which regulate the immune system and enhance immune tolerance after transplantation. Donor-derived Treg prevent the development of lethal acute graft-versus-host disease (GVHD) in murine models of allogeneic hematopoietic stem...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Nishikii, Hidekazu, Kim, Byung-Su, Yokoyama, Yasuhisa, Chen, Yan, Baker, Jeanette, Pierini, Antonio, Alvarez, Maite, Mavers, Melissa, Maas-Bauer, Kristina, Pan, Yuqiong, Chiba, Shigeru, Negrin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159706/
https://ncbi.nlm.nih.gov/pubmed/27760760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-06-723783
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