Regular Aspirin Use Associates with Lower Risk of Colorectal Cancers With Low Numbers of Tumor-infiltrating Lymphocytes

BACKGROUND & AIMS: Aspirin use reduces colorectal cancer risk. Aspirin, a nonsteroidal anti-inflammatory drug, inhibits PTGS2 (cyclooxygenase-2); PTGS2 promotes inflammation and suppresses T cell-mediated adaptive immunity. We investigated whether the inverse association of aspirin use with colo...

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Detaylı Bibliyografya
Yayımlandı:Gastroenterology
Asıl Yazarlar: Cao, Yin, Nishihara, Reiko, Qian, Zhi Rong, Song, Mingyang, Mima, Kosuke, Inamura, Kentaro, Nowak, Jonathan A., Drew, David A., Lochhead, Paul, Nosho, Katsuhiko, Morikawa, Teppei, Zhang, Xuehong, Wu, Kana, Wang, Molin, Garrett, Wendy S., Giovannucci, Edward L., Fuchs, Charles S., Chan, Andrew T., Ogino, Shuji
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159194/
https://ncbi.nlm.nih.gov/pubmed/27475305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.07.030
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