Regular Aspirin Use Associates with Lower Risk of Colorectal Cancers With Low Numbers of Tumor-infiltrating Lymphocytes

BACKGROUND & AIMS: Aspirin use reduces colorectal cancer risk. Aspirin, a nonsteroidal anti-inflammatory drug, inhibits PTGS2 (cyclooxygenase-2); PTGS2 promotes inflammation and suppresses T cell-mediated adaptive immunity. We investigated whether the inverse association of aspirin use with colo...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Cao, Yin, Nishihara, Reiko, Qian, Zhi Rong, Song, Mingyang, Mima, Kosuke, Inamura, Kentaro, Nowak, Jonathan A., Drew, David A., Lochhead, Paul, Nosho, Katsuhiko, Morikawa, Teppei, Zhang, Xuehong, Wu, Kana, Wang, Molin, Garrett, Wendy S., Giovannucci, Edward L., Fuchs, Charles S., Chan, Andrew T., Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159194/
https://ncbi.nlm.nih.gov/pubmed/27475305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2016.07.030
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