Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell Lines

Autophagy, a self-digestive system for cytoplasmic components, is required to maintain the amino acid pool for cellular homeostasis. We previously reported that the macrolide antibiotics azithromycin (AZM) and clarithromycin (CAM) have an inhibitory effect on autophagy flux, and they potently enhanc...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Hirasawa, Kazuhiro, Moriya, Shota, Miyahara, Kana, Kazama, Hiromi, Hirota, Ayako, Takemura, Jun, Abe, Akihisa, Inazu, Masato, Hiramoto, Masaki, Tsukahara, Kiyoaki, Miyazawa, Keisuke
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5158196/
https://ncbi.nlm.nih.gov/pubmed/27977675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164529
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares