Amino acid starvation culture condition sensitizes EGFR-expressing cancer cell lines to gefitinib-mediated cytotoxicity by inducing atypical necroptosis

The maintenance of the intracellular level of amino acids is crucial for cellular homeostasis. This is carried out via the regulation of both the influx from the extracellular environment and the recycling of intracellular resources. Since epidermal growth factor receptor (EGFR)-tyrosine kinase inhi...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Saito, Yu, Moriya, Shota, Kazama, Hiromi, Hirasawa, Kazuhiro, Miyahara, Kana, Kokuba, Hiroko, Hino, Hirotsugu, Kikuchi, Hiroyuki, Takano, Naoharu, Hiramoto, Masaki, Tsukahara, Kiyoaki, Miyazawa, Keisuke
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843391/
https://ncbi.nlm.nih.gov/pubmed/29484439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4282
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