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Induction of synergistic non-apoptotic cell death by simultaneously targeting proteasomes with bortezomib and histone deacetylase 6 with ricolinostat in head and neck tumor cells

Following surgery and chemoradiation, ~50% of patients with locally advanced head and neck tumors experience relapse within the first two years, with a poor prognosis. Therefore, a novel therapeutic approach is required. The aim of the present study was to investigate the effect of combination treat...

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Dettagli Bibliografici
Pubblicato in:Oncol Lett
Autori principali: Hattori, Kazuhiro, Takano, Naoharu, Kazama, Hiromi, Moriya, Shota, Miyake, Keitaro, Hiramoto, Masaki, Tsukahara, Kiyoaki, Miyazawa, Keisuke
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8323012/
https://ncbi.nlm.nih.gov/pubmed/34345305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12941
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