Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells

Antzeko izenburuak

• Clarithromycin enhances bortezomib-induced cytotoxicity via endoplasmic reticulum stress-mediated CHOP (GADD153) induction and autophagy in breast cancer cells
  nork: KOMATSU, SEIICHIRO, et al.
  Argitaratua: (2011)
• Macrolide Antibiotics Exhibit Cytotoxic Effect under Amino Acid-Depleted Culture Condition by Blocking Autophagy Flux in Head and Neck Squamous Cell Carcinoma Cell Lines
  nork: Hirasawa, Kazuhiro, et al.
  Argitaratua: (2016)
• Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress-mediated cell death in multiple myeloma cells
  nork: MORIYA, SHOTA, et al.
  Argitaratua: (2014)
• Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines
  nork: Miyahara, Kana, et al.
  Argitaratua: (2016)
• Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization-associated cell death
  nork: Takeda, Atsuo, et al.
  Argitaratua: (2020)