Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress-mediated cell death in multiple myeloma cells

The inhibitory effects of macrolide antibiotics including clarithromycin (CAM) on autophagy flux have been reported. Although a macrolide antibiotic exhibits no cytotoxicity, its combination with bortezomib (BZ), a proteasome inhibitor, for the simultaneous blocking of the ubiquitin (Ub)-proteasome...

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Publicado no:Int J Oncol
Main Authors: MORIYA, SHOTA, KOMATSU, SEIICHIRO, YAMASAKI, KAHO, KAWAI, YUSUKE, KOKUBA, HIROKO, HIROTA, AYAKO, CHE, XIAO-FANG, INAZU, MASATO, GOTOH, AKIHIKO, HIRAMOTO, MASAKI, MIYAZAWA, KEISUKE
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4277245/
https://ncbi.nlm.nih.gov/pubmed/25422130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2773
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