Synthesis of a Ribose‐Incorporating Medium Ring Scaffold via a Challenging Ring‐Closing Metathesis Reaction

A practical synthesis of a novel oxabicyclo[6.2.1]undecenetriol useful as a medicinal chemistry scaffold has been developed starting from l‐ribose. The sequence involves an oxidation/Grignard addition sequence and a challenging ring‐closing metathesis (RCM) reaction as the ring forming step. Explora...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:European J Org Chem
Main Authors: Rankin, Stuart S., Caldwell, John J., Cronin, Nora B., van Montfort, Rob L. M., Collins, Ian
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Full Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157775/
https://ncbi.nlm.nih.gov/pubmed/28042283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201600756
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares