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Spiro annulation of cage polycycles via Grignard reaction and ring-closing metathesis as key steps

A simple synthetic strategy to C(2)-symmetric bis-spiro-pyrano cage compound 7 involving ring-closing metathesis is reported. The hexacyclic dione 10 was prepared from simple and readily available starting materials such as 1,4-naphthoquinone and cyclopentadiene. The synthesis of an unprecedented oc...

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Bibliografiske detaljer
Udgivet i:Beilstein J Org Chem
Main Authors: Kotha, Sambasivarao, Saifuddin, Mohammad, Ali, Rashid, Sreevani, Gaddamedi
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4578432/
https://ncbi.nlm.nih.gov/pubmed/26425191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.147
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