Загрузка...
Non-monotonic dynamics and crosstalk in signaling pathways and their implications for pharmacology
Currently, drug discovery approaches commonly assume a monotonic dose-response relationship. However, the assumption of monotonicity is increasingly being challenged. Here we show that for two simple interacting linear signaling pathways that carry two different signals with different physiological...
Сохранить в:
| Опубликовано в: : | Sci Rep |
|---|---|
| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2015
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5155565/ https://ncbi.nlm.nih.gov/pubmed/26087464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11376 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|