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Theory for the optimal detection of time-varying signals in cellular sensing systems

Living cells often need to measure chemical concentrations that vary in time, yet how accurately they can do so is poorly understood. Here, we present a theory that fully specifies, without any adjustable parameters, the optimal design of a canonical sensing system in terms of two elementary design...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Malaguti, Giulia, ten Wolde, Pieter Rein
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7946427/
https://ncbi.nlm.nih.gov/pubmed/33594978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62574
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