Caricamento...

Deferoxamine Suppresses Collagen Cleavage and Protease, Cytokine, and COL10A1 Expression and Upregulates AMPK and Krebs Cycle Genes in Human Osteoarthritic Cartilage

This study reports the effects of the iron chelator deferoxamine (DFO) on collagen cleavage, inflammation, and chondrocyte hypertrophy in relation to energy metabolism-related gene expression in osteoarthritic (OA) articular cartilage. Full-depth explants of human OA knee articular cartilage from ar...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Int J Rheumatol
Autori principali: Tchetina, Elena V., Markova, Galina A., Poole, A. Robin, Zukor, David J., Antoniou, John, Makarov, Sergey A., Kuzin, Aleksandr N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155111/
https://ncbi.nlm.nih.gov/pubmed/28042296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6432867
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !