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The Anti-Aging and Tumor Suppressor Protein Klotho Enhances Differentiation of a Human Oligodendrocytic Hybrid Cell Line

Klotho functions as an aging suppressor, which, in mice, extends lifespan when overexpressed and accelerates development of aging-like phenotypes when disrupted. Klotho is mainly expressed in brain and kidney and is secreted into the serum and CSF. We have previously shown that Klotho is reduced in...

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Veröffentlicht in:J Mol Neurosci
Hauptverfasser: Chen, Ci-Di, Li, Hu, Liang, Jennifer, Hixson, Kathryn, Zeldich, Ella, Abraham, Carmela R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154549/
https://ncbi.nlm.nih.gov/pubmed/24907942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-014-0336-1
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