The Antiaging Protein Klotho Enhances Oligodendrocyte Maturation and Myelination of the CNS

We have previously shown that myelin abnormalities characterize the normal aging process of the brain and that an age-associated reduction in Klotho is conserved across species. Predominantly generated in brain and kidney, Klotho overexpression extends life span, whereas loss of Klotho accelerates t...

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Detalhes bibliográficos
Main Authors: Chen, Ci-Di, Sloane, Jacob A., Li, Hu, Aytan, Nurgul, Giannaris, Eustathia L., Zeldich, Ella, Hinman, Jason D., Dedeoglu, Alpaslan, Rosene, Douglas L., Bansal, Rashmi, Luebke, Jennifer I., Kuro-o, Makoto, Abraham, Carmela R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711388/
https://ncbi.nlm.nih.gov/pubmed/23365232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2080-12.2013
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