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Peptide- and Amine-Modified Glucan Particles for the Delivery of Therapeutic siRNA

Translation of siRNA technology into the clinic is limited by the need for improved delivery systems that target specific cell types. Macrophages are particularly attractive targets for RNAi therapy because they promote pathogenic inflammatory responses in a number of important human diseases. We pr...

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Dades bibliogràfiques
Publicat a:Mol Pharm
Autors principals: Cohen, Jessica L., Shen, Yuefei, Aouadi, Myriam, Vangala, Pranitha, Tencerova, Michaela, Amano, Shinya U., Nicoloro, Sarah M., Yawe, Joseph C., Czech, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153885/
https://ncbi.nlm.nih.gov/pubmed/26815386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00831
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