Lipid storage by adipose tissue macrophages regulates systemic glucose tolerance

Proinflammatory pathways in adipose tissue macrophages (ATMs) can impair glucose tolerance in obesity, but ATMs may also be beneficial as repositories for excess lipid that adipocytes are unable to store. To test this hypothesis, we selectively targeted visceral ATMs in obese mice with siRNA against...

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Autors principals: Aouadi, Myriam, Vangala, Pranitha, Yawe, Joseph C., Tencerova, Michaela, Nicoloro, Sarah M., Cohen, Jessica L., Shen, Yuefei, Czech, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137117/
https://ncbi.nlm.nih.gov/pubmed/24986598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00187.2014
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