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Lipid storage by adipose tissue macrophages regulates systemic glucose tolerance

Proinflammatory pathways in adipose tissue macrophages (ATMs) can impair glucose tolerance in obesity, but ATMs may also be beneficial as repositories for excess lipid that adipocytes are unable to store. To test this hypothesis, we selectively targeted visceral ATMs in obese mice with siRNA against...

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Detalles Bibliográficos
Main Authors: Aouadi, Myriam, Vangala, Pranitha, Yawe, Joseph C., Tencerova, Michaela, Nicoloro, Sarah M., Cohen, Jessica L., Shen, Yuefei, Czech, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137117/
https://ncbi.nlm.nih.gov/pubmed/24986598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00187.2014
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