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Lipid storage by adipose tissue macrophages regulates systemic glucose tolerance
Proinflammatory pathways in adipose tissue macrophages (ATMs) can impair glucose tolerance in obesity, but ATMs may also be beneficial as repositories for excess lipid that adipocytes are unable to store. To test this hypothesis, we selectively targeted visceral ATMs in obese mice with siRNA against...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137117/ https://ncbi.nlm.nih.gov/pubmed/24986598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00187.2014 |
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