Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation

Adipose tissue (AT) of obese mice and humans accumulates immune cells, which secrete cytokines that can promote insulin resistance. AT macrophages (ATMs) are thought to originate from bone marrow-derived monocytes, which infiltrate the tissue from the circulation. Here we show that a major fraction...

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Bibliografske podrobnosti
Main Authors: Amano, Shinya U., Cohen, Jessica L., Vangala, Pranitha, Tencerova, Michaela, Nicoloro, Sarah M., Yawe, Joseph C., Shen, Yuefei, Czech, Michael P., Aouadi, Myriam
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931314/
https://ncbi.nlm.nih.gov/pubmed/24374218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.11.017
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