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Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation
Adipose tissue (AT) of obese mice and humans accumulates immune cells, which secrete cytokines that can promote insulin resistance. AT macrophages (ATMs) are thought to originate from bone marrow-derived monocytes, which infiltrate the tissue from the circulation. Here we show that a major fraction...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3931314/ https://ncbi.nlm.nih.gov/pubmed/24374218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.11.017 |
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