PrP(C) Association with Lipid Rafts in the Early Secretory Pathway Stabilizes Its Cellular Conformation

The pathological conversion of cellular prion protein (PrP(C)) into the scrapie prion protein (PrP(Sc)) isoform appears to have a central role in the pathogenesis of transmissible spongiform encephalopathies. However, the identity of the intracellular compartment where this conversion occurs is unkn...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sarnataro, Daniela, Campana, Vincenza, Paladino, Simona, Stornaiuolo, Mariano, Nitsch, Lucio, Zurzolo, Chiara
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Cell Biology 2004
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC515338/
https://ncbi.nlm.nih.gov/pubmed/15229281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-05-0271
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