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Cytosolically expressed PrP GPI-signal peptide interacts with mitochondria
We previously reported that PrP GPI-anchor signal peptide (GPI-SP) is specifically degraded by the proteasome. Additionally, we showed that the point mutation P238S, responsible for a genetic form of prion diseases, while not affecting the GPI-anchoring process, results in the accumulation of PrP GP...
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| Publicado no: | Commun Integr Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4594234/ https://ncbi.nlm.nih.gov/pubmed/26480298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420889.2015.1036206 |
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