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Doppel and PrP(C) co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells

Dpl (doppel) is a paralogue of the PrP(C) (cellular prion protein), whose misfolded conformer (the scrapie prion protein, PrP(Sc)) is responsible for the onset of TSEs (transmissible spongiform encephalopathies) or prion diseases. It has been shown that the ectopic expression of Dpl in the brains of...

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書誌詳細
主要な著者: Caputo, Anna, Sarnataro, Daniela, Campana, Vincenza, Costanzo, Maddalena, Negro, Alessandro, Sorgato, M. Catia, Zurzolo, Chiara
フォーマット: Artigo
言語:Inglês
出版事項: Portland Press Ltd. 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825736/
https://ncbi.nlm.nih.gov/pubmed/19888917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091050
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