Doppel and PrP(C) co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells

Dpl (doppel) is a paralogue of the PrP(C) (cellular prion protein), whose misfolded conformer (the scrapie prion protein, PrP(Sc)) is responsible for the onset of TSEs (transmissible spongiform encephalopathies) or prion diseases. It has been shown that the ectopic expression of Dpl in the brains of...

Full description

Saved in:
Bibliographic Details
Main Authors: Caputo, Anna, Sarnataro, Daniela, Campana, Vincenza, Costanzo, Maddalena, Negro, Alessandro, Sorgato, M. Catia, Zurzolo, Chiara
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825736/
https://ncbi.nlm.nih.gov/pubmed/19888917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091050
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items