Doppel and PrP(C) co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells

Dpl (doppel) is a paralogue of the PrP(C) (cellular prion protein), whose misfolded conformer (the scrapie prion protein, PrP(Sc)) is responsible for the onset of TSEs (transmissible spongiform encephalopathies) or prion diseases. It has been shown that the ectopic expression of Dpl in the brains of...

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Detalhes bibliográficos
Main Authors: Caputo, Anna, Sarnataro, Daniela, Campana, Vincenza, Costanzo, Maddalena, Negro, Alessandro, Sorgato, M. Catia, Zurzolo, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825736/
https://ncbi.nlm.nih.gov/pubmed/19888917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20091050
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