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Conformational Properties of β-PrP
Prion propagation involves a conformational transition of the cellular form of prion protein (PrP(C)) to a disease-specific isomer (PrP(Sc)), shifting from a predominantly α-helical conformation to one dominated by β-sheet structure. This conformational transition is of critical importance in unders...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2755922/ https://ncbi.nlm.nih.gov/pubmed/19369250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809173200 |
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