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p21-Mediated Nuclear Retention of Cyclin B1-Cdk1 in Response to Genotoxic Stress

G2 arrest of cells suffering DNA damage in S phase is crucial to avoid their entry into mitosis, with the concomitant risks of oncogenic transformation. According to the current model, signals elicited by DNA damage prevent mitosis by inhibiting both activation and nuclear import of cyclin B1-Cdk1,...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Charrier-Savournin, Fabienne Baus, Château, Marie-Thérèse, Gire, Véronique, Sedivy, John, Piette, Jacques, Dulić, Vjekoslav
פורמט: Artigo
שפה:Inglês
יצא לאור: The American Society for Cell Biology 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC515331/
https://ncbi.nlm.nih.gov/pubmed/15181148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-12-0871
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