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Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1)

Cell-cycle phase transitions are controlled by cyclin-dependent kinases (Cdks). Key to the regulation of these kinase activities are Cdk inhibitors, proteins that are induced in response to various antiproliferative signals but that can also oscillate during cell-cycle progression, leading to Cdk in...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Hengst, Ludger, Göpfert, Ulrich, Lashuel, Hilal A., Reed, Steven I.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317274/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9869641/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.24.3882
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