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The cyclin dependent kinase inhibitor p21Cip1/Waf1 is a therapeutic target in high-risk neuroblastoma

Platinum-based chemotherapies such as cisplatin are used as first-line treatment for the paediatric tumour neuroblastoma. Although the majority of neuroblastoma tumours respond to therapy, there is a high fraction of high-risk neuroblastoma patients that eventually relapse with increased resistance....

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Autori principali: Agnes Luise Sorteberg, Vesa Halipi, Malin Wickström, Shahrzad Shirazi Fard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2022-09-01
Serie:Frontiers in Oncology
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Accesso online:https://www.frontiersin.org/articles/10.3389/fonc.2022.906194/full
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