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Permanent cell cycle exit in G(2) phase after DNA damage in normal human fibroblasts

Although the Cdk inhibitor p21(Waf1/Cip1), one of the transcriptional targets of p53, has been implicated in the maintenance of G(2) arrest after DNA damage, its function at this stage of the cell cycle is not really understood. Here, we show that the exposure of normal human fibroblasts (NHFs) to g...

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Autors principals: Baus, Fabienne, Gire, Véronique, Fisher, Daniel, Piette, Jacques, Dulić, Vjekoslav
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC169060/
https://ncbi.nlm.nih.gov/pubmed/12881433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg387
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