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Cdk2 strengthens the intra-S checkpoint and counteracts cell cycle exit induced by DNA damage
Although cyclin-dependent kinase 2 (Cdk2) controls the G1/S transition and promotes DNA replication, it is dispensable for cell cycle progression due to redundancy with Cdk1. Yet Cdk2 also has non-redundant functions that can be revealed in certain genetic backgrounds and it was reported to promote...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5647392/ https://ncbi.nlm.nih.gov/pubmed/29044141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12868-5 |
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